2011 Lung Cancer Research Foundation Annual Grant Program
Puneeth Iyengar, MD, PhD
University of Texas Southwestern Medical Center
Research Project:
A Comparative Genomics/Proteomics Approach with In Vivo Small Animal Validation for Developing a Signature to Predict for Cachexia-Inducing Non-Small Cell Lung Cancers
Summary:
Cachexia is a condition associated with many lung cancers characterized by significant weight loss, appetite decrease and overall weakness. This condition is often associated with lower rates of treatment response compared to other patients. The grant will use animal models to study potential predictive markers for the condition which could lead to clinical preventative measures in such patients during the cancer treatment period.