2011 Lung Cancer Research Foundation Annual Grant Program
Erica Bell, PhD
The Ohio State University
Research Project:
Understanding Common Alterations in Chromatin Remodeling Pathways in Lung Cancer and their Correlation to Treatment Response
Summary:
This grant will study the mutation involving BRG1 which has been described in 20-30% lung cancers. The abnormality will be evaluated in terms of its impact on cancer cell growth and also how it affects the response to drugs for the treatment of lung cancer. Further knowledge of this mutation may lead to specific treatment recommendations for patients with this mutation.