2011 Lung Cancer Research Foundation Annual Grant Program
Christina Addison, PhD
Ottawa Hospital Research Institute
Research Project:
Towards Effective Therapies for EGFR Wild-Type Non-Small Cell Lung Cancer
Summary:
90% of patients with lung cancer have high levels of EGFR yet the majority do not have significant response to EGFR inhibitors. This grant will study some of the co-factors responsible for blocking the expected effects. Knowledge of the presence and action of these co-factors could be used to identify patients who are not candidates for such therapy and lead to alternative options.