2013 Lung Cancer Research Foundation Annual Grant Program
Brendon Stiles, MD
Weill Cornell Medical College
Research Project:
Identification and therapeutic targeting of CD44-high/CD24-low tumors in non-small cell lung cancer
Summary:
The purpose of Dr. Stiles’s proposal is to confirm activation of the IL-6/JAK-STAT in clinical specimens of CD44-high/CD24-low NSCLC tumors; explore treatment paradigms based upon IL-6/JAK inhibition for these tumors; and assess clinical biomarkers for further classification of these tumors.