2014 Lung Cancer Research Foundation Annual Grant Program
Tammela Tuomas, MD, PhD
Massachusetts Institute of Technology
Research Project:
Modification of Lung Cancers Toward a More Drug-Responsive State
Summary:
This study will test the role of the Wnt pathway in lung tumor initiation and progression, as well as the potential target of therapy. Dr. Tammela and his team will use small molecule inhibitors of Wnt synthesis or dual-promoter lentiviruses to silence key components of the pathway using RNAi.