2008 Free to Breathe Career Development Award
I-Ching Wang, PhD
Cincinnati Children's Hospital Medical Center
Research Project:
Regulating Cell Growth
Summary:
Dr. Wang seeks to understand how FoxM1, a protein that helps regulate cell growth in normal cells, may also contribute to uncontrolled growth in cancerous cells. Although FoxM1 is known to play a role in the development of lung cancer, the exact mechanisms by which it is acting are not yet defined. Dr. Wang’s research seeks to define FoxM1’s actions in lung cancer initiation, ultimately to help facilitate development of novel therapies directed towards the protein.