2008 Free to Breathe Young Investigator Research Grant
Lee Goodglick, PhD
University of California, Los Angeles
Research Project:
Effect of Estrogen on Lung Tumors
Summary:
Dr. Goodglick will focus on how estrogen may drive some lung tumors to grow and become more deadly. Aromatase-inhibitor drugs, which have long been used to treat breast cancer by decreasing estrogen levels in patients, will be studied in pre-clinical models to determine their effectiveness in treating lung cancer. Additional research will use new technologies to study lung tumor tissues to determine other steps in the estrogen stimulation pathway that affect tumor progression.