2010 Lung Cancer Research Foundation Annual Grant Program
James Welsh, MD
University of Texas MD Anderson Cancer Center
Research Project:
Developing a New Method of Reducing Resistance to Lung Cancer Therapy
Summary:
Recent discoveries have identified a potential way that lung cancer cells not only become resistant to treatment with radiation or drugs, but also develop an ability to develop metastases. This proposal will study that mechanism in detailed models with the aim of applying this new information to techniques to reduce resistance of the cancer to effective therapy but also to potentially block the development of distant sites of disease.