2010 Lung Cancer Research Foundation Annual Grant Program
John Heymach, MD, PhD
University of Texas MD Anderson Cancer Center
Research Project:
Understanding What Genetic Mutations in Lung Cancer are Functionally Important
Summary:
There has been a large increase in genetic mutations identified in lung cancer cells compared to normal cells. Many of these gene changes are inter-related and dependent upon each other. This grant request proposes to apply a technique that could characterize the most significant gene alterations that affect cell function and growth. If successful, this could potentially lead to better stratification and prioritization of gene targets for research in lung cancer.