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Previously Funded Research

2011 Lung Cancer Research Foundation Annual Grant Program

Donald Kufe

Donald Kufe, MD

Dana-Farber Cancer Institute

Research Project:

Targeting the MUC1-C Oncoprotein in Drug Resistant NSCLC

Summary:

This grant extends previous LCRF support to study the MUC-1 oncoprotein, which is often found in high levels in lung cancer that are associated with shorter survival and resistance to common current treatments. Inhibitors to MUC-1 will be now evaluated in animal models and early human clinical trials to see if they are effective in decreasing the growth of these aggressive cancers.

Donald Kufe