2011 Lung Cancer Research Foundation Annual Grant Program
James Welsh, MD
University of Texas MD Anderson Cancer Center
Research Project:
Circulating miR-200 family as biomarker of resistance to radiation and erlotinib in lung cancer
Summary:
Recent research has identified a potential way in which lung cancer cells not only become resistant to treatment with radiation or drugs, but also how they develop the ability to metastasize. Dr. Welsh’s research studied those mechanisms in detailed models, with the aim of applying this new information to reduce therapeutic resistance and to potentially block the development of distant sites of disease.