2012 Lung Cancer Research Foundation Annual Grant Program
Pang-Dian Fan,
Memorial Sloan Kettering Cancer Center
Research Project:
Identification of novel mechanisms of resistance to ALK inhibitors using transpoon-tagged insertional mutagensis in EML4-ALK-dependent lung adenocarcinoma cell lines
Summary:
Grant will study mechanisms of resistance to an approved treatment for lung cancer called ALK inhibition. If successful, the scientific model that is being developed in this study could lead to effective standard application of this analytic method in additional settings.