2014 Lung Cancer Research Foundation Annual Grant Program
Ross Cagan, PhD
Icahn School of Medicine Mount Sinai
Research Project:
Embracing Genetic Complexity in Personalized Fly Models of Lung Cancer
Summary:
In this study, Dr. Cagan will use the fruit fly, Drosophila, to generate 15 lung cancer ‘patient avatars’ with each fly line reflecting the exomic sequencing of a single patient. Focusing on patients with mutations in EGFR family members, he will use these avatars to explore differences in tumor progression between tumors with different genomic profiles.