2014 Lung Cancer Research Foundation Annual Grant Program
Christine Hann, MD, PhD
Johns Hopkins University
Research Project:
Developing a New Combined Targeted Therapy Treatment of Patients with Small Cell Lung Cancer (SCLC)
Summary:
Dr. Hann will use Bcl-2, Bcl-xL or dual Bcl-2/Bcl-xL specific small molecule inhibitors (“BH3-mimetics”) to determine whether targeting Bcl-2 or both Bcl-2 and Bcl-xL is required for the observed synergy of this combination. If successful, this work could lead to new and more effective treatment for patients with SCLC.