2014 Lung Cancer Research Foundation Annual Grant Program
Linde Miles,
Memorial Sloan Kettering Cancer Center
Research Project:
Complementary Screening Approaches to Identify Host Receptors of an Important Lung Cancer Targeting Virus
Summary:
This project focuses around a virus that selectively infects and kills small cell lung cancer (SCLC) cells while sparing normal cells. The goal of the project is to identify the proteins important in viral infection using techniques that create libraries of cells with gene knockouts — and subsequently protein knockouts — of every gene in the human genome.