2014 Lung Cancer Research Foundation Annual Grant Program
Warren Denning, PhD
University of Texas MD Anderson Cancer Center
Research Project:
CAR Modified T Cells as a Novel Immunotherapy to Eliminate Lung Cancer
Summary:
Dr. Denning’s research focus is investigating immunotherapeutic targets in lung cancer. Specifically, he is studying alterations in immune response in various mutational subsets of lung cancer; epithelial-to-mesenchymal transition; and the acquisition of therapeutic-resistance during lung cancer progression. The Lung Cancer Research Foundation is supporting his work investigating the immune system in small cell lung cancer (SCLC), an aggressive malignancy accounting for around 15% of newly diagnosed lung cancer. Dr. Denning is the recipient of the 2014 Scientific Merit Award.